18 NovAdam M. Roseman, Adam Roseman
Nine years ago, Cedars-Sinai Medical Center’s Maxine Dunitz Neurosurgical Institute discovered a small change which occurs in the molecular structure of the most violent type of brain tumor; the glioblastoma multiforme. When they dug deeper, they detected that a specific protein called laminin- 411 supports the building of the tumor’s new blood vessels, which enable its widespread growth. At the time, there was no technology available that could block this protein.
Recently, a research team from Cedars-Sinai, which is a non-profit organization where Adam Roseman is a board member, has created a drug which is injected into the bloodstream and carried to the tumor. The drug is triggered by the different pH level in the cancerous cells, and blocks the tumor cells’ production of the harmful laminin-411 protein. This new method is regarded as the first of its kind.